Genetic Aberrancies and Neurodegenerative Disorders

Genetic Aberrancies and Neurodegenerative Disorders

Mattson, M. P.; Geddes, James W.

Elsevier Science & Technology

10/1999

427

Dura

Inglês

9780762304059

15 a 20 dias

Presents reviews and findings concerning the roles of genetic mutations and polymorphisms in the pathogenesis of a range of neurological disorders including Alzheimer's and Parkinson's diseases, trinucleotide repeat disorders, stroke, epilepsy and others.
Contents. List of Contributors. Preface (M.P. Mattson). Genetic Contributions to the Pathogenesis of Alzeheimer's Disease (M.P. Mattson). The Biology of Trinucleotide Repeat Disorders (P.H. Reddy and D.A. Tagle). The Genetic Basis and Molecular Pathogenesis of Huntington's Disease (N.W. Kowall, S. Kuemmerle, and R.J. Ferrante). Genetic Abnormalities in Amyotrophic Lateral Sclerosis (E.J. Kasarskis and D.K. St. Clair). Human Prion Diseases (B. Ghetti and P. Gambetti). Progress in Understanding the Genetics of Epilepsy (C.E. Stafstrom, A.N. Prasad, C. Prasad, and J.T. Slevin). Cerebrovascular Disease (L. Penix, and D. Lanska). Genetic Susceptibility in Multiple Sclerosis (R.B. Bell). The Role of Mitochondrial Genome Mutations in Neurodegenerative Disease (G.W. Glazner). Hereditary Disorders of Copper Metabolism (Z. Tumer and N. Horn). The Neuronal Ceroid-Lipofuscinoses Batten Disease (R.D. Jolly, A. Kohlschutter, D.N. Palmer, and S.U. Walkley). Index.
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